Description

What is Spedra?

Buy Spedra Online is the trade name for a drug called Avanafil. Spedra is one of a class of drugs known as PDE-5 (Phosphodiesterase type 5) inhibitors. Spedra and the other PDE-5 inhibitors can help men with erectile dysfunction (male impotence) by enhancing the erectile response when a man is sexually stimulated. Aside from Spedra, the other drugs in this class are Viagra, Cialis (Tadalafil) and Levitra (Vardenafil).

How does Spedra work?

Buy Spedra Online does not cause a man to be sexually aroused, it is only effective if you are sexually aroused.

To understand how it works you need to understand the mechanics of how a man gets an erection.  The nitric oxide stimulates an enzyme that produces something called a messenger cyclic guanosine monophosphate (cGMP).

The cGMP relaxes the smooth muscle cells. One result of this is that the arteries in your penis dilate and the blood can flow into your penis more easily. Another result is that the erectile tissue itself fills with blood. Both of these process result in an erection.

Spedra works by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina.

This maintains the level of cGMP in the smooth muscle cells.

If  not turned on, your brain will not stimulate the release of any nitric oxide and you will not produce any cGMP.

Is Spedra effective?

Clinical studies have shown that when compared to placebo, Spedra and the other drugs in the same class, result in significant improvement in erectile function.

The claimed advantage of Spedra is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes. About two-thirds of the participants in trials were able to engage in sexual activity within 15 minutes.

Throughout all trials of Spedra, statistically significant improvements in all primary efficacy outcomes were observed for all three doses (50mg, 100mg and 200mg) of avanafil compared with placebo. These were maintained with long-term treatment.

Although establish to be a safe and effective drug, Spedra isn’t appropriate for everyone and may not work in all cases.